MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome

What this Trial Is About

Carpal tunnel syndrome (CTS) causes pain, numbness, or tingling in the hand and wrist due to pressure on the median nerve. This trial evaluates two surgical approaches for adults with CTS: standard surgery releasing only the carpal tunnel, and extended surgery releasing both the carpal tunnel and the Lacertus fibrosus, a ligament higher in the arm that may also compress the nerve. The study aims to find which surgery better reduces symptoms and improves patient outcomes. Participants will be randomly assigned to one of two groups. One group will receive the standard carpal tunnel release surgery, which involves cutting the transverse carpal ligament to relieve nerve pressure. The other group will undergo an extended surgery that also releases the Lacertus fibrosus by making an additional incision near the elbow to decompress the median nerve further. Both procedures are outpatient and done under local anesthesia. During the 12 months after surgery, participants will be followed regularly. Researchers will assess symptoms using the Boston Carpal Tunnel Questionnaire and monitor functional status, pain, sensation, strength, work ability, complications, and quality of life. They will also track if any participants need additional surgery. The study includes physical exams and patient questionnaires throughout the follow-up period to evaluate recovery and treatment effects.

MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome