Actively Recruiting
Comparison of Upper and Lower Limb Maximal Exercise Capacities and Arterial Stiffness in Patients With CAD
Led by Gazi University · Updated on 2026-02-03
30
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Coronary artery disease (CAD) significantly increases mortality rates in both developed and developing countries. In this condition, the impairment of arterial blood circulation leads to insufficient blood supply to the myocardium during both rest and exercise, resulting in symptoms such as angina pectoris, dyspnea, and fatigue. Patients, particularly due to their fear of experiencing angina pectoris, tend to adopt a sedentary lifestyle. This situation contributes to exercise intolerance and a reduction in exercise capacity among individuals with CAD. A review of the literature reveals a lack of studies investigating upper and lower extremity exercise capacity and the physiological responses during exercise testing in patients with CAD. Therefore, the aim of this study is to compare arterial stiffness, muscle oxygenation, respiratory muscle fatigue, energy expenditure, perceived dyspnea, and fatigue during upper and lower extremity exercise testing in patients with coronary artery disease.
CONDITIONS
Official Title
Comparison of Upper and Lower Limb Maximal Exercise Capacities and Arterial Stiffness in Patients With CAD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-85 with coronary artery disease diagnosed by conventional or CT angiography
- Clinically stable
- Willing to participate
You will not qualify if you...
- Heart failure diagnosis
- Moderate/severe valvular heart disease
- Orthopedic, neurological, or pulmonary conditions limiting exercise testing or capacity
- Contraindications according to ACSM guidelines
- Prior coronary artery bypass graft surgery
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Gazi University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit, Ankara, Çankaya 06490
Ankara, Çankaya, Turkey (Türkiye), 06490
Actively Recruiting
Research Team
M
Meral BOŞNAK GÜÇLÜ, Prof. Dr.
CONTACT
N
Naciye SEVİM, Pt.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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