Actively Recruiting
Complex Arrhythmia Registry (CAR): Long-term Outcomes of Catheter Ablation for Atrial Fibrillation or Ventricular Tachycardia in a Multicenter Prospective Cohort Study
Led by Beijing Anzhen Hospital · Updated on 2026-06-04
4000
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the long-term outcomes of catheter ablation for treating atrial fibrillation (AF) and ventricular tachycardia (VT) in Chinese patients. This prospective, non-randomized, multicenter observational registry study aims to systematically assess the effectiveness and safety of advanced radiofrequency ablation techniques. It focuses on redefining AF recurrence relationships and optimizing treatment strategies using AF burden, while also assessing novel technologies in VT treatment. The study includes two cohorts: an AF cohort and a VT cohort. Catheter ablation procedures are performed using 3D mapping systems. For AF, pulmonary vein isolation is mandatory, with ablation strategies tailored by physicians. For VT, detailed mapping techniques identify critical regions for targeted ablation. The study observes patients undergoing first-time ablation with treatments delivered under general or local anesthesia. Participants will be monitored for freedom from atrial arrhythmia over 12 months following ablation, excluding a 3-month blanking period, and for composite outcomes including VT recurrence, cardiovascular hospitalization, or death during the same follow-up. Data collection involves clinical assessments, documentation of arrhythmia episodes, and safety monitoring. The registry provides important long-term safety and efficacy data over a minimum 12-month period, with follow-up visits to capture outcomes up to June 2032.
CONDITIONS
Brief Title
Complex Arrhythmia Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with atrial fibrillation (paroxysmal or persistent) or ventricular tachycardia associated with structural heart disease
- Scheduled for first-time catheter ablation using a 3D mapping system
- Willing and able to provide signed informed consent
- Able to comply with all required follow-up assessments
You will not qualify if you...
- Severe congenital heart disease (e.g., Tetralogy of Fallot, corrected transposition of the great arteries)
- Atrial fibrillation or ventricular tachycardia caused by clearly reversible factors (e.g., hyperthyroidism, acute myocardial ischemia)
- Unstable angina or acute myocardial infarction within 30 days before procedure
- Severe active infection such as septic shock or sepsis
- Contraindications to anticoagulation therapy
- Current participation in another interventional clinical trial that may affect results
- Cardiac surgery within 60 days before planned ablation
- Severe coagulopathy or very low heart function (left ventricular ejection fraction below 20%)
- Any condition judged by investigators as unsuitable for participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of the procedure
Participants undergo catheter ablation procedures for atrial fibrillation or ventricular tachycardia using advanced radiofrequency ablation technologies and 3D mapping systems.
1 visit (in-person)
Duration - Up to 12 months
Participants are monitored for long-term outcomes including recurrence of arrhythmia, cardiovascular hospitalization, or death following the ablation procedure.
Periodic follow-up visits during 12 months
Trial Site Locations
Total: 2 locations
1
No. 2 Anzhen Rd, Chaoyang District, 100029
Beijing, Beijing Municipality, China, 100029
Actively Recruiting
2
Beijing Anzhen Hospital, Capital Medical University
Beijing, China
Not Yet Recruiting
Research Team
D
Deyong Long, MD
D
Deyong Long
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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