Study of Swallowing Rehabilitation Treatment for Adults with Multiple System Atrophy

What this Trial Is About

Multiple system atrophy MSA is a fast-progressing disease affecting movement and autonomic functions, often leading to swallowing difficulties known as dysphagia. This research evaluates the effects of a comprehensive swallowing rehabilitation program in patients with MSA to improve swallowing safety and efficiency. The study compares this approach to swallowing education alone, aiming to address dysphagia regardless of the MSA subtype. Participants receive either comprehensive swallowing rehabilitation, which includes functional muscle training, compensatory swallowing techniques, and thermal-tactile stimulation, or a single session of swallowing education. The rehabilitation involves twelve 30-minute sessions over six weeks, while the education group receives a single 30-minute session after the initial evaluation. During the study, participants undergo assessments including videofluoroscopic swallowing studies and various measures of respiratory and swallowing function at 6 and 12 weeks. Researchers monitor the Penetration-Aspiration Scale and Videofluoroscopic Dysphagia Scale as primary outcomes at 6 weeks, along with secondary outcomes such as cough strength, respiratory pressures, lung function, phonation time, and quality of life related to swallowing. The study continues with follow-up evaluations to assess changes over time and participant safety.

Comprehensive Swallowing Rehabilitation in Patients With MSA