Study of Brainwave Patterns and Risk of Delirium After Surgery in Patients 65 and Older
Led by Xin Chen · Updated on 2026-04-16
90
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying whether multiscale entropy analysis of electroencephalogram EEG data can help distinguish between ordinary elderly surgical patients and those who develop postoperative delirium. The study aims to identify postoperative delirium early in patients aged 65 and older undergoing surgery with general anesthesia. The sponsor leading this observational study is Xin Chen.
Participants will have their EEG data collected before and during surgery using a device called Neuron-Spectrum-5-1. The study focuses on elderly patients undergoing general anesthesia with specific airway management criteria. There are no drug treatments involved as this is an observational study that monitors brain activity to find patterns linked to delirium.
During the study, researchers will observe participants for signs of postoperative delirium within seven days after surgery. They will analyze the EEG data collected and monitor patients closely to evaluate the incidence of delirium. Participation includes EEG recording and standard surgical care, with follow-up assessments to track delirium symptoms during the first week after surgery.
CONDITIONS
Brief Title
Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.
Research Team
F
Fu Dr.chen
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Second Affiliated Hospital of Hainan Medical College
Collaborating Sponsor
Who Can Participate
Age: 65Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Patients undergoing general anaesthesia with single-lumen endotracheal tube placement
Age 65 years or older, any gender, body mass index (BMI) 18-28 kg/m²
Normal mouth opening and head/neck mobility
Pre-anaesthesia ASA physical status classification of I or II and Mallampati airway classification of I or II
You will not qualify if you...
Individuals with psychiatric disorders, literacy issues, or communication difficulties unable to cooperate with delirium screening
Severe lesions in vital organs such as heart, lungs, brain, liver, or kidneys
Undergoing cardiac or neurosurgical procedures during this admission
History of alcohol abuse or recent use of sedatives or opioids
Hemoglobin less than 100 g/L
Participation in any clinical research studies within the past 3 months
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Implementation
Duration - Day of surgery
Participants undergo general anesthesia while preoperative and intraoperative electroencephalogram data are collected using the Neuron-Spectrum-5-1 device.
1 visit (in-person)
Post-operative Follow-up
Duration - 7 days
Participants are monitored for the incidence of postoperative delirium within seven days after surgery.
Daily assessments for up to 7 days post-surgery
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Processed Multiparameter Electroencephalogram-Guided General Anesthesia Management Can Reduce Postoperative Delirium Following Carotid Endarterectomy: A Randomized Clinical Trial.
Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients.