Actively Recruiting
Corticosteroids to Treat Pancreatitis
Led by Beth Israel Deaconess Medical Center · Updated on 2026-02-18
86
Participants Needed
1
Research Sites
264 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research is being done to determine if the administration of a short course of intravenous hydrocortisone, an anti-inflammatory medication, to patients with severe acute pancreatitis will improve their clinical outcomes and decrease the length of hospitalization. We think that because inflammation in the body drives the progression of pancreatitis, giving a short course of intravenous hydrocortisone may mitigate disease progression and improve clinical outcomes in patients with severe acute pancreatitis.
CONDITIONS
Official Title
Corticosteroids to Treat Pancreatitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult (≥18 years)
- Clinical diagnosis of acute pancreatitis with a lipase level ≥3 times the upper limit of normal
- Admission or planned admission to an intensive care unit
- SOFA disease severity score ≥3 or at least 3 points above a known baseline
You will not qualify if you...
- Known diagnosis of autoimmune pancreatitis
- Existing clinical need for corticosteroids at doses greater than 5 mg oral prednisone daily or equivalent
- Contraindication to receiving corticosteroids
- Prisoners or other protected populations
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
M
Michael Donnino, MD
CONTACT
K
Katherine Berg, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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