Targeting Suicidality in Young Adults: a Randomized, Controlled Pragmatic, Multicentre Trial Evaluating the (Cost)-Effectiveness of Attachment Based Family Therapy Compared to Treatment as Usual
Led by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Updated on 2024-08-22
138
Participants Needed
13
Research Sites
52 weeks
Total Duration
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Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lead Sponsor
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KU Leuven
Collaborating Sponsor
AI-Summary
What this Trial Is About
Young adults aged 18 to 25 who experience frequent thoughts about killing themselves are the focus of this study, which evaluates the (cost-)effectiveness of Attachment Based Family Therapy (ABFT) compared to Treatment As Usual (TAU). Suicide is a leading cause of death among young adults, and current treatments have limited success. This trial aims to determine if involving family through ABFT can better reduce suicidality and improve outcomes, informing clinical guidelines and care practices in Belgium and the Netherlands.
Participants are randomly assigned to one of two groups: the experimental group receives ABFT as an add-on to TAU, which includes treatments like antidepressants, CBT, or DBT, with weekly ABFT sessions lasting about 16 weeks. The control group receives TAU alone, allowing up to four sessions of systemic family therapy. ABFT focuses on strengthening parent-child attachment bonds to provide a supportive base for young adults, involving parents or caregivers actively in therapy.
Throughout the study, suicidality is measured at baseline, immediately after intervention, and at follow-ups 3, 6, and 12 months post-intervention using tools like the Suicidal Ideation Questionnaire Junior. Researchers also assess depressive symptoms, family functioning, attachment, quality of life, and healthcare costs. The trial includes 138 participants across multiple sites, with double-blind randomized allocation. Safety, adherence, and cost-effectiveness are closely monitored during and after the treatment period.
CONDITIONS
Brief Title
(Cost)-Effectiveness of ABFT for Suicidal Youth.
Who Can Participate
Age: 18Years - 25Years
All Genders
Eligibility Criteria
You may qualify if you...
Aged between 18 and 25.
Score above 31 on the Suicidal Ideation Questionnaire Junior.
Have at least one primary parent or caregiver who participates in assessment and treatment (biological parent, stepparent, grandparent, other relative, or foster parent).
You will not qualify if you...
Severe alcohol or cannabis use disorder, or modest/severe substance use disorder for other substances.
Severe conduct disorder.
Evidence of psychotic features or prior psychosis.
Severe cognitive impairment such as mental retardation or severe developmental disorders.
Other circumstances affecting participation, such as severe medical disorders or relocation.
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Outpatient Treatment
Duration - Approximately 16 weeks
Participants receive weekly sessions of Attachment Based Family Therapy (ABFT) as an add-on to their usual care, or continue with Treatment As Usual (TAU) alone to address suicidality. The therapy focuses on strengthening family relationships and attachment bonds.
Weekly visits for up to 16 weeks
Follow-up
Duration - Up to 12 months after treatment
Participants are monitored after treatment ends to assess the longer-term effects on suicidality, depressive symptoms, family functioning, and other outcomes.
The effectiveness and cost-effectiveness of attachment-based family therapy for young adults with high suicidal ideation: protocol of a randomized controlled trial.