Actively Recruiting
D Vitamin and Alveolar Macrophages in Idiopathic Pulmonal Fibrosis
Led by University of Aarhus · Updated on 2025-04-03
120
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the role of human macrophages and vitamin D in people with Idiopathic Pulmonary Fibrosis (IPF). The study aims to understand whether patients with IPF have low vitamin D levels in their blood and lungs, and whether their lung macrophages promote fibrosis and inflammation. This observational research is sponsored by the University of Aarhus and focuses on gaining deeper insights into these factors in IPF and related lung diseases. Participants in this study include patients diagnosed with IPF, non-IPF interstitial lung disease, or lung cancer. There are no specific treatment interventions as this is an observational study. The study collects blood and bronchoalveolar lavage (BAL) samples to measure biomarker levels, vitamin D status, and analyze pulmonary macrophages at enrollment. During the study, participants undergo assessments at enrollment to evaluate vitamin D levels and lung macrophage characteristics. Blood and BAL samples are collected for biomarker analysis. The study seeks to better understand disease mechanisms by comparing these measures across different lung conditions. Participation involves providing informed consent and attending study visits for sample collection and assessments. The study started in October 2024 and will continue until October 2026.
CONDITIONS
Brief Title
D Vitamin and Alveolar Macrophages in Idiopathic Pulmonal Fibrosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A clinical diagnosis of IPF, non-IPF ILD or lung cancer
- A signed informed consent
You will not qualify if you...
- Do not speak Danish/Do not understand Danish
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of enrollment
Participants undergo assessments including measurement of Vitamin D status and pulmonary macrophages at enrollment.
1 visit (in-person)
Duration - Up to 5 years
Participants are observed over time to monitor biomarker levels and disease status without active intervention.
Visits as per routine clinical care
Trial Site Locations
Total: 1 location
1
Aarhus University Hospital, Denmark
Aarhus N, Denmark, 8200
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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