Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
ID06756230

Effects of Downhill Walking in Pulmonary Rehabilitation for Patients With Idiopathic Pulmonary Fibrosis

Led by Saglik Bilimleri Universitesi · Updated on 2025-05-16

34

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effects of downhill walking, a type of eccentric exercise training, on exercise capacity, quality of life, and blood lactate levels in adults with idiopathic pulmonary fibrosis (IPF). Participants will be randomly assigned to either a downhill walking pulmonary rehabilitation group or a standard pulmonary rehabilitation group to compare outcomes. The study involves two groups: one will perform downhill walking on a treadmill set at a constant -10% incline, while the other will follow a standard treadmill walking program without incline. Both groups will participate in pulmonary rehabilitation sessions twice a week for eight weeks. Each session includes aerobic treadmill walking for 30 minutes within a target heart rate range of 60-80% intensity, monitored by blood pressure, heart rate, and perceived exertion scores, along with warm-up, stretching, and resistance exercises tailored to individual patient conditions. Participants will be assessed at the start and end of the eight-week program using several measures including the 6-minute walking distance and the Saint George quality of life questionnaire as primary outcomes. Secondary evaluations include lung function tests, muscle strength, dyspnea scores, fatigue severity, anxiety and depression levels, blood lactate levels, and carbon monoxide diffusion capacity. This comprehensive monitoring aims to understand how downhill walking impacts physical function and well-being in people with IPF.

CONDITIONS

Brief Title

Downhill Walking in IPF

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of idiopathic pulmonary fibrosis according to American Thoracic Society and/or European Respiratory Society criteria
  • Age between 18 and 75 years
  • Ability to walk on a treadmill
  • Ability to cooperate with study procedures
  • No change in current medication in the last month
  • Not participating in any structured activity program for at least six months
  • Voluntary acceptance of study purpose and method with informed consent
Not Eligible

You will not qualify if you...

  • Physical or mental impairment preventing informed consent or protocol compliance
  • Inability to attend more than 80% of pulmonary rehabilitation sessions
  • Major cardiovascular diseases such as coronary artery disease, uncontrolled hypertension, arrhythmias, or heart failure
  • Orthopedic or neuromuscular exercise limitations
  • Recent acute exacerbation of condition

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 8 weeks

Participants receive pulmonary rehabilitation involving treadmill walking exercises either downhill or on a flat treadmill, along with warm-up, stretching, and resistance exercises tailored to their condition.

2 sessions per week

Trial Site Locations

Total: 1 location

1

Saglik Bilimleri Universitesi

Istanbul, Üsküdar, Turkey (Türkiye), 34668

Actively Recruiting

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Research Team

E

Esra PEHLIVAN, Associate Professor

N

Nisanur TUTUŞ

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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