Actively Recruiting
Effects of Downhill Walking in Pulmonary Rehabilitation for Patients With Idiopathic Pulmonary Fibrosis
Led by Saglik Bilimleri Universitesi · Updated on 2025-05-16
34
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate the effects of downhill walking, a type of eccentric exercise training, on exercise capacity, quality of life, and blood lactate levels in adults with idiopathic pulmonary fibrosis (IPF). Participants will be randomly assigned to either a downhill walking pulmonary rehabilitation group or a standard pulmonary rehabilitation group to compare outcomes. The study involves two groups: one will perform downhill walking on a treadmill set at a constant -10% incline, while the other will follow a standard treadmill walking program without incline. Both groups will participate in pulmonary rehabilitation sessions twice a week for eight weeks. Each session includes aerobic treadmill walking for 30 minutes within a target heart rate range of 60-80% intensity, monitored by blood pressure, heart rate, and perceived exertion scores, along with warm-up, stretching, and resistance exercises tailored to individual patient conditions. Participants will be assessed at the start and end of the eight-week program using several measures including the 6-minute walking distance and the Saint George quality of life questionnaire as primary outcomes. Secondary evaluations include lung function tests, muscle strength, dyspnea scores, fatigue severity, anxiety and depression levels, blood lactate levels, and carbon monoxide diffusion capacity. This comprehensive monitoring aims to understand how downhill walking impacts physical function and well-being in people with IPF.
CONDITIONS
Brief Title
Downhill Walking in IPF
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic pulmonary fibrosis according to American Thoracic Society and/or European Respiratory Society criteria
- Age between 18 and 75 years
- Ability to walk on a treadmill
- Ability to cooperate with study procedures
- No change in current medication in the last month
- Not participating in any structured activity program for at least six months
- Voluntary acceptance of study purpose and method with informed consent
You will not qualify if you...
- Physical or mental impairment preventing informed consent or protocol compliance
- Inability to attend more than 80% of pulmonary rehabilitation sessions
- Major cardiovascular diseases such as coronary artery disease, uncontrolled hypertension, arrhythmias, or heart failure
- Orthopedic or neuromuscular exercise limitations
- Recent acute exacerbation of condition
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants receive pulmonary rehabilitation involving treadmill walking exercises either downhill or on a flat treadmill, along with warm-up, stretching, and resistance exercises tailored to their condition.
2 sessions per week
Trial Site Locations
Total: 1 location
1
Saglik Bilimleri Universitesi
Istanbul, Üsküdar, Turkey (Türkiye), 34668
Actively Recruiting
Research Team
E
Esra PEHLIVAN, Associate Professor
N
Nisanur TUTUŞ
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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