Actively Recruiting
Prevalence and Characteristics of Dental and Periodontal Lesions in Patients With Sjögren's Syndrome and Establishment of a Biological Saliva Collection
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-12-30
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying Sjögren's syndrome (SS), a rare autoimmune disease that damages the glands that produce saliva. This condition can lead to dry mouth, which may increase the risk of dental problems like tooth wear, inflammation, and gum recession. The study aims to understand how common these dental and gum issues are in people with SS and how they relate to saliva changes and oral quality of life. This observational study collects saliva samples and dental assessments from patients with Sjögren's syndrome during their regular visits to the oral medicine department. The saliva samples will be stored for future research. The study will follow patients annually for five years to measure dental wear, gum recession, gum inflammation, and tooth decay, along with saliva characteristics like dryness, flow rates, pH, and buffering capacity. Participants will have yearly evaluations for five years as part of their routine care, including dental exams and saliva tests. Researchers will analyze the prevalence of dental and gum problems and explore connections between oral health, saliva quality, and patients' quality of life. The study will last a total of ten years, including five years of patient follow-up, to help better understand oral health challenges in Sjögren's syndrome.
CONDITIONS
Brief Title
Dental and Periodontal Status of Patients With Sjögren's Syndrome.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with Sjögren Syndrome
- Patient older than 18 years
- Patient affiliated to a social security system or beneficiary of a similar right
- Patient who speaks and understands French well enough to read and understand the study information
- Patient who does not object to participation in the study
You will not qualify if you...
- Patient having expressed opposition to participate in the research
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 5 years
Participants who undergo routine care are observed with annual assessments of dental wear, gingival recession, salivary parameters, and oral quality of life.
Annual visits for 5 years
Duration - 5 years
Participants continue under observation for long-term outcomes related to dental and periodontal status.
Annual visits for 5 years
Trial Site Locations
Total: 1 location
1
Service de Médecine bucco-dentaire
Ivry-sur-Seine, Île-de-France Region, France, 94200
Actively Recruiting
Research Team
M
Marjolaine GOSSET, PU-PH
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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