Actively Recruiting
Intraoperative Dermabrasion in Mohs Surgery: A Randomized Split-Scar Trial to Evaluate Scar Appearance
Led by University of Wisconsin, Madison · Updated on 2025-10-31
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating how intraoperative dermabrasion affects scar appearance after Mohs Micrographic Surgery (MMS) on the face or neck. The study aims to find out if gently removing the top layer of skin during surgery improves the way scars look after healing. This study will enroll 50 participants and last up to 6 months, focusing on scar healing and appearance. Participants will have their surgical wound divided into two sides, labeled A and B. One side will receive dermabrasion treatment during surgery, where a scratch pad is used along the wound edge until slight bleeding occurs, while the other side will not. Both sides will be closed with stitches as usual. The side receiving dermabrasion is randomly chosen for each participant, and the procedure does not add extra surgery time. During the study, researchers will assess scars at 3 months after surgery using the Patient and Observer Scar Assessment Scale (POSAS), including both observer and patient scores and overall patient opinion of the scar. They will also track any complications. Participants must return for follow-up visits, and the study includes safety monitoring over the 6-month period.
CONDITIONS
Brief Title
Dermabrasion in Mohs: Split-Scar Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to give informed consent themselves
- Scheduled for cutaneous surgical procedure on the face or neck with predicted linear closure greater than 4 centimeters
- Willing to return for follow up visit within the evaluation period
You will not qualify if you...
- Patients with impaired decision-making capacity
- Significant vision or hearing impairments
- Pregnant Individuals
- Incarceration
- Wounds with predicted closure length less than 4 cm
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery
Participants undergo Mohs surgery with intraoperative dermabrasion applied to one side of the wound as randomized.
1 visit (in-person)
Duration - 3 months post-surgery
Participants return for scar assessment and evaluation of complications at 3 months after surgery.
1 follow-up visit (in-person)
Trial Site Locations
Total: 1 location
1
UW Health Mohs Surgery Clinic
Madison, Wisconsin, United States, 53717
Actively Recruiting
Research Team
D
Dermatology Research
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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