Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05950282

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

Led by Ali Chappell · Updated on 2026-05-01

150

Participants Needed

1

Research Sites

199 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The study aims to investigate the relationship between fasting insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) across various demographic factors, including age, sex, race/ethnicity, BMI, and polycystic ovary syndrome (PCOS) diagnosis. By analyzing these variables, the study seeks to identify potential variations in insulin levels, which could provide valuable insights into the impact of different factors on metabolic health and the development of insulin-related conditions.

CONDITIONS

Official Title

Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged 18 or older
  • Both males and females
  • Participants from diverse racial and ethnic backgrounds
  • Participants across a range of body mass index (BMI) values
  • Participants with and without a confirmed diagnosis of PCOS based on established diagnostic criteria
  • Completion of metabolic testing within one month prior to enrollment, including fasting insulin, hemoglobin A1c, complete lipid panel, and triglycerides
  • Laboratory testing completed through a healthcare provider, independent laboratory, or using an Insara Insulin Testing Kit
  • Laboratory values obtained following a minimum 8-hour fast
  • Complete laboratory data available for all required measures
Not Eligible

You will not qualify if you...

  • Participants under 18 years of age
  • Presence of other endocrine disorders affecting insulin levels (e.g., insulin-secreting tumors)
  • Recent weight loss exceeding 5% of body weight within the previous month
  • Pregnancy or breastfeeding
  • Acute illness or infection within the past 2 weeks
  • Use of medications known to significantly affect insulin or glucose metabolism (these will be recorded and considered in analysis)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Lilli Health

Houston, Texas, United States, 77554

Actively Recruiting

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Research Team

A

Ali M Chappell, PhD, MS, RD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis | DecenTrialz