Actively Recruiting

All Genders
ID04937868

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

Led by University of California, Los Angeles · Updated on 2026-01-13

12000

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

B

Brigham and Women's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Unrecognized abdominal and pelvic injuries from blunt trauma can lead to serious disability or death. Physicians often use computed tomography (CT) scans on many blunt trauma patients to avoid missing injuries, but this exposes many patients to radiation and high costs while finding injuries in only a few. Researchers are evaluating a decision tool to identify "low-risk" patients who may safely avoid CT imaging without missing significant injuries, aiming to reduce unnecessary scans, radiation exposure, and healthcare costs. This observational study involves adult blunt trauma patients who receive abdominal-pelvic CT scans in the emergency department. Physicians will record clinical signs and symptoms such as pain, tenderness, bruising, vital signs, and injury mechanism before imaging. The study will develop and validate decision instruments to classify patients as high or low risk for major or minor abdominal and pelvic injuries based on these clinical findings, without altering standard medical care. Participants will undergo routine clinical evaluations and CT imaging as part of their emergency care. Researchers will analyze the presence or absence of injuries using CT results and patient outcomes to assess the accuracy of the decision instruments. The main outcomes are the instruments' ability to correctly identify major and minor injuries. The study aims to confirm that these tools can safely reduce CT imaging, lowering radiation exposure and costs while maintaining patient safety.

CONDITIONS

Brief Title

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Blunt trauma patients who undergo abdominal-pelvic CT imaging during their initial trauma evaluation in the emergency department.
Not Eligible

You will not qualify if you...

  • None

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo initial emergency department evaluation where clinicians assess clinical criteria prior to abdominal-pelvic CT imaging.

1 visit (in-person)

Monitoring

Duration - Up to the index visit duration

Participants are observed based on final radiologic interpretation of the initial CT imaging and clinical care during their index visit to determine injury classification and outcomes.

Follow-up visits as part of routine care

Trial Site Locations

Total: 1 location

1

Ronald Reagan Hospital

Los Angeles, California, United States, 90024

Actively Recruiting

Loading map...

Research Team

W

William R Mower, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Similar Trials

A Randomized Controlled Trial of Abdominal Ultrasound (FAST)...

Blunt Trauma to Abdomen

Actively Recruiting

6 locations

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Predictors for the selection of patients for abdominal CT after blunt trauma: a proposal for a diagnostic algorithm.

Jaap Deunk, Monique Brink, Helena M Dekker...

https://pubmed.ncbi.nlm.nih.gov/20083993

Clinical prediction rules for identifying adults at very low risk for intra-abdominal injuries after blunt trauma.

James F Holmes, David H Wisner, John P McGahan...

https://pubmed.ncbi.nlm.nih.gov/19457583