Intra-abdominal injury following blunt trauma. Identifying the high-risk patient using objective risk factors.
R C Mackersie, A D Tiwary, S R Shackford...
https://pubmed.ncbi.nlm.nih.gov/2742481/Actively Recruiting
Led by University of California, Los Angeles · Updated on 2026-01-13
12000
Participants Needed
1
Research Sites
21 weeks
Total Duration
Unrecognized abdominal and pelvic injuries from blunt trauma can lead to serious disability or death. Physicians often use computed tomography CT scans on many blunt trauma patients to avoid missing injuries, but this exposes many patients to radiation and high costs while finding injuries in only a few. Researchers are evaluating a decision tool to identify low-risk patients who may safely avoid CT imaging without missing significant injuries, aiming to reduce unnecessary scans, radiation exposure, and healthcare costs. This observational study involves adult blunt trauma patients who receive abdominal-pelvic CT scans in the emergency department. Physicians will record clinical signs and symptoms such as pain, tenderness, bruising, vital signs, and injury mechanism before imaging. The study will develop and validate decision instruments to classify patients as high or low risk for major or minor abdominal and pelvic injuries based on these clinical findings, without altering standard medical care. Participants will undergo routine clinical evaluations and CT imaging as part of their emergency care. Researchers will analyze the presence or absence of injuries using CT results and patient outcomes to assess the accuracy of the decision instruments. The main outcomes are the instruments ability to correctly identify major and minor injuries. The study aims to confirm that these tools can safely reduce CT imaging, lowering radiation exposure and costs while maintaining patient safety.
CONDITIONS
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
W
William R Mower, MD, PhD
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University of California, Los Angeles
Lead Sponsor
Brigham and Women's Hospital
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo initial emergency department evaluation where clinicians assess clinical criteria prior to abdominal-pelvic CT imaging.
1 visit (in-person)
Duration - Up to the index visit duration
Participants are observed based on final radiologic interpretation of the initial CT imaging and clinical care during their index visit to determine injury classification and outcomes.
Follow-up visits as part of routine care
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Lead Sponsor
Brigham and Women's Hospital
Collaborating Sponsor