Actively Recruiting
Developing Viability Index for Machine Perfused Livers
Led by Massachusetts General Hospital · Updated on 2025-11-03
60
Participants Needed
1
Research Sites
608 weeks
Total Duration
On this page
Sponsors
M
Massachusetts General Hospital
Lead Sponsor
B
Brigham and Women's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Machine perfusion technology is nearing the point of rescuing discarded liver grafts in the hope of proving them to be or improving them to the point of being transplantable. However, there are no validated metrics to determine transplantability after machine perfusion. This study involves collecting biopsies from transplanted livers before and after implantation to correlate metabolite and gene expression with post-transplant function. This data will help develop a viability index for machine perfused livers.
CONDITIONS
Official Title
Developing Viability Index for Machine Perfused Livers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female 18-75 years of age
- Candidate for a deceased-donor liver allograft
You will not qualify if you...
- Seropositivity for HIV-1
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
H
Heidi Yeh, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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