Actively Recruiting
Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis
Led by University Hospital, Bonn · Updated on 2022-05-18
200
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying non-invasive methods to characterize focal liver lesions in patients with liver cirrhosis. The study evaluates the diagnostic accuracy and predictive value of these imaging techniques compared to standard methods like CT, MRI, or histology. This research aims to better understand how well non-invasive tests can detect and predict outcomes in liver cirrhosis cases. The study uses multiparametric ultrasound imaging, including B-Mode ultrasound, Duplex sonography, contrast-enhanced ultrasound, and elastography, along with measurements of sarcopenia parameters for lesion characterization. Standard diagnostic procedures such as CT, MRI, and anthropometric assessments are also performed. All diagnostic workup, treatment, and follow-up occur as part of usual care. Participants undergo these imaging and diagnostic tests, and researchers analyze the results for diagnostic accuracy over one year and predictive value for mortality and treatment response up to five years. The study involves monitoring participants with liver cirrhosis and focal liver lesions, with no experimental treatments applied. Participation length varies depending on follow-up for outcome measures.
CONDITIONS
Brief Title
Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- All patients with focal liver lesions and liver cirrhosis
You will not qualify if you...
- No consent
- Under 18 years old or younger than 18 years old or below age 18 years old
- Patients who do not provide consent to participate in the study or withdraw consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - At diagnosis
Participants undergo multiparametric ultrasound imaging and other standard diagnostic procedures to characterize focal liver lesions.
1 visit (in-person)
Duration - Up to 5 years
Participants are observed with standard of care work up, treatment, and follow up to assess diagnostic accuracy and predictive value of non-invasive methods.
Trial Site Locations
Total: 1 location
1
University Hospital Bonn
Bonn, Germany
Actively Recruiting
Research Team
M
Michael Praktiknjo, MD
J
Johannes Chang, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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