Actively Recruiting
Diagnosis and Outcomes of Placental Accretism
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-02-19
70
Participants Needed
7
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the current main criteria used to diagnose placenta accreta and studying the maternal outcomes related to different management strategies for suspected placental accretism. The goal is to better understand the complications and improve standardization of care for affected pregnant women aged 18 to 44 years. This observational study is both retrospective and prospective and conducted across multiple centers nationally. Patients will receive treatment based on usual clinical practice. The study will collect and analyze key imaging and instrumental findings from cases of suspected accretism. It will compare outcomes between conservative management (cesarean section with placenta left in place) and more radical management (cesarean section with concurrent hysterectomy). Monitoring includes vital signs, laboratory tests, ultrasound, and other examinations during pregnancy, immediate postpartum, and follow-up visits. Participants will have visits twice a week during pregnancy unless complications arise. Postpartum follow-up depends on the procedure performed and any complications. Researchers will assess the agreement between prenatal diagnosis and surgical findings, as well as maternal complications such as surgical site infection up to one month after delivery. No questionnaires or rating scales are used. The study runs until December 31, 2026.
CONDITIONS
Brief Title
Diagnosis and Outcomes of Placental Accretism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 years and 44 years
- Pregnant women with suspected placental accretism
- Acquisition of informed consent form
You will not qualify if you...
- None
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 to 2 visits depending on assessment of suspected placental accretism
Duration - Up to delivery (variable length)
Participants who undergo routine care are observed during pregnancy with clinical assessments including vital parameters, laboratory tests, ultrasound images, and instrumental examinations to evaluate progression.
Approximately twice weekly visits during pre-partum
Duration - Up to hospital discharge (variable length)
Participants undergoing cesarean section with either conservative management (placenta in situ) or radical management (cesarean section with hysterectomy) are monitored during the immediate post-operative period.
Visits as per clinical care during hospital stay
Duration - Up to 1 month post-partum
Participants are followed up after discharge to assess maternal and fetal outcomes, including the occurrence of complications and recovery, through outpatient visits and clinical assessments.
Outpatient follow-up visits depending on procedure and complications
Trial Site Locations
Total: 7 locations
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy, 40138
Actively Recruiting
2
Ospedale "M. Bufalini"
Cesena, Forlì-Cesena, Italy, 47521
Actively Recruiting
3
Ospedale "Morgagni-Pierantoni"
Forlì, Forlì-Cesena, Italy, 47121
Actively Recruiting
4
AOU Policlinico di Modena
Modena, Modena, Italy, 41100
Actively Recruiting
5
Azienda Ospedaliero - Universitaria di Parma
Parma, Parma, Italy, 43126
Actively Recruiting
6
Arcispedale Santa Maria Nuova
Reggio Emilia, Reggio Emilia, Italy, 42123
Actively Recruiting
7
Ospedale "Infermi" di Rimini
Rimini, Rimini, Italy, 47900
Actively Recruiting
Research Team
G
Gianluigi Pilu, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here