Actively Recruiting
Digital Biofeedback for Combat Veterans Diagnosed With PTSD
Led by NeuroBrave ltd. · Updated on 2026-03-10
80
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized controlled trial (RCT) will evaluate the effectiveness of a digital biofeedback-based intervention ("Mental Gym®") designed to reduce Posttraumatic Stress Disorder (PTSD) symptoms and improve mental health. The intervention combines daily HRV biofeedback exercises using a wearable device (Garmin watch), a dedicated mobile application, and weekly group guidance sessions. A delayed-intervention control group design will be used. To account for expected attrition and ensure a final sample of 60 participants, approximately 80 subjects will be recruited. Physiological and self-report data will be collected pre- and post-intervention, weekly during the intervention, and at follow-ups (3 months post-intervention). The study population consists of combat veterans diagnosed with PTSD.
CONDITIONS
Official Title
Digital Biofeedback for Combat Veterans Diagnosed With PTSD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male sex
- Age 18 years and older
- Clinical diagnosis of PTSD with mild to moderate-severe symptoms
- PCL-5 total score up to 60 at screening
- PTSD diagnosis based on a traumatic event from year 2000 or later
- Eligibility for Ministry of Defense rehabilitation services
- Ability to use a smartphone and wearable device
You will not qualify if you...
- PTSD symptom severity above moderate-severe range (PCL-5 score > 60) or needing intensive clinical intervention
- Acute psychiatric instability including active suicidal thoughts or psychosis
- Current use of Olanzapine (Zyprexa) or Quetiapine (Seroquel)
- Severe sleep impairment (Insomnia Severity Index score > 7)
- Severe concentration or cognitive impairment preventing use of digital biofeedback tools
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
NeuroBrave LTD - Remote Site
Jerusalem, Israel
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here