Actively Recruiting

Age: 18Years - 70Years
All Genders
NCT07422844

Dynamic Network Response to TMS Treatment

Led by Goethe University · Updated on 2026-02-20

100

Participants Needed

1

Research Sites

318 weeks

Total Duration

On this page

Sponsors

G

Goethe University

Lead Sponsor

U

University of Giessen

Collaborating Sponsor

AI-Summary

What this Trial Is About

This project aims to investigate whether symptom and brain networks and TMS stimulation sites can predict the response to TMS treatment of a transdiagnostic patient group with depressive syndrome. The TMS treatment is no intervention study - the investigators aim to observe patients who receive TMS as part of their psychiatric treatment. Additionally, the investigators aim to investigate exploratively how symptoms change over the course of treatment with TMS, that is, which symptoms respond first to treatment. Patients participate in a separate study first (DYNAMIC Central Project, registered with the German Clinical Trials Register: DRKS00038256), where MRI data is acquired. Within this project the symptomatology before, during and after the TMS-treatment are observed.

CONDITIONS

Official Title

Dynamic Network Response to TMS Treatment

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients treated with TMS as an antidepressant will be recruited.
  • Both men and women will be included in a balanced ratio.
  • Participants must have German language skills to complete questionnaires, interviews, and instructions.
Not Eligible

You will not qualify if you...

  • Patients younger than 18 or older than 70 years.
  • Participants who did not participate in the DYNAMIC central project (DRKS00038256).
  • Acute or chronic neurological diseases.
  • Pregnancy.
  • Lack of access to internet-enabled devices needed for app-based questionnaires.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Klinik für Psychiatrie, Psychosomatik und Psychotherapie

Frankfurt am Main, Hesse, Germany, 60528

Actively Recruiting

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Research Team

J

Jonathan Repple, Prof. Dr. med.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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