Actively Recruiting
NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status
Led by National Science and Technology Council, Taiwan · Updated on 2026-02-27
50
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
Sponsors
N
National Science and Technology Council, Taiwan
Lead Sponsor
F
Fondation FondaMental
Collaborating Sponsor
AI-Summary
What this Trial Is About
A 12-week, randomized, placebo-controlled trial testing the efficacy of n-3 PUFA treatment (EPA, 2 g/day) in alleviating depressive symptoms in a subgroup of obese subjects with comorbid depression and low n-3 PUFA status (n-3 index \< 8%) (81), from the Taiwanese cohort. Associations with PLA2/COX2 genotypes, lifestyle, nutritional profiles and gut microbiota will also be determined.
CONDITIONS
Official Title
NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids Status
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Major depressive disorder
- Antidepressant drug-free
- Age between 18 and 54 years
You will not qualify if you...
- Schizophrenia
- Mania
- Anxiety disorders (except social phobia and generalized anxiety)
- Obsessive-compulsive disorder
- Post-traumatic stress disorder
- Alcohol or drug abuse/dependence (except nicotine)
- Active suicidal ideation
- Serious medical or neurological conditions requiring corticosteroid, non-steroidal anti-inflammatory, immunosuppressive therapies, or chronic thyroid hormone replacement
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mind Body Interface Research Center (MBI Lab & Care)
Taichung, Taichung, Taiwan, 404
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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