Actively Recruiting

Age: 50Years - 100Years
All Genders
NCT05943834

Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)

Led by Centre Hospitalier Universitaire de Nice · Updated on 2026-03-19

100

Participants Needed

1

Research Sites

221 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

PLATA aims to develop an algorithm to identify vocal biomarkers of Alzheimer's dementia. Using data collected as part of routine care, speech patterns will be compared to known biomarkers of Alzheimer's disease, such as amyloid 1-42 and p-Tau in CSF (cerebrospinal fluid). If biomarkers of speech can be identified in Alzheimer's disease, it is possible that patients and research participants will no longer need to undergo need to undergo the intensive and invasive baseline biomarker methods currently used, such as lumbar punctures and PET scans.

CONDITIONS

Official Title

Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)

Who Can Participate

Age: 50Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age �3E= 50 years
  • Diagnosis relevant biomarker and neuropsychological data already available
  • Cognitively healthy to very mild dementia (CDR score max. 0.5)
  • Sufficient knowledge of the study language to understand study information, non opposition form, and questionnaires
  • Expression of non opposition
Not Eligible

You will not qualify if you...

  • Hearing problems
  • Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Nice

Nice, France, 06100

Actively Recruiting

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Research Team

E

Eric ETTORE, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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