Actively Recruiting
Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
Led by University of Texas at Austin · Updated on 2025-01-16
90
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand racial differences in cardiovascular health by studying vascular function in healthy African American, Hispanic, and Caucasian American adults. The study focuses on how vascular function may vary among these groups and investigates the effects of nitrate supplementation on blood flow and vascular health. Participants include healthy adults aged 18 to 65 years without major health issues or medications that might affect vascular function. Participants will take part in a randomized, placebo-controlled study where they consume either 140 ml of beetroot juice, a high nitrate dietary supplement, or a placebo drink that looks and tastes like beetroot juice but without nitrates. Each participant will undergo two visits separated by at least one week, measuring vascular function before and 90 minutes after consuming the assigned drink. The study uses a triple-blind design to ensure unbiased results. During the study, researchers will measure forearm blood flow and flow-mediated vasodilation to assess vascular function. These measurements will occur through study completion, averaging about two years. Participants’ blood pressure and health status are monitored to ensure safety. The study involves healthy volunteers and includes regular assessments of vascular responses to the interventions to better understand potential benefits across racial groups.
CONDITIONS
Brief Title
Effect of Acute Nitrate Supplementation on Vascular Function in Hispanic, Black and White Population
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy men and women who are either Caucasian American, Hispanic, or non-Hispanic African American
- Age between 18 and 65 years
You will not qualify if you...
- Blood pressure higher than or equal to 140/90 mmHg
- Body mass index greater than 35 kg/m2
- History of cardiovascular, neurological, or vascular diseases
- Taking prescription medications
- Smoking
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 2 weeks
Participants consume beetroot juice (high nitrate supplement) or placebo drink in a randomized crossover design, with vascular function measured before and 90 minutes after intake. There is at least a 1-week washout period between the two visits.
2 visits (in-person), each including pre- and post-consumption assessments
Trial Site Locations
Total: 1 location
1
University of Texas at Austin
Austin, Texas, United States, 78712
Actively Recruiting
Research Team
J
jasdeep kaur, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here