Actively Recruiting
Effect of Blood Flow Restriction on Recovery After Maximal Resistance Exercise: a Controlled Clinical Trial
Led by Paulista University · Updated on 2026-01-15
80
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how blood flow restriction (BFR) techniques may help improve recovery after intense resistance exercise. The study involves healthy adults aged 18 to 35 years and aims to compare different BFR pressures to understand their effects on muscle recovery, pain, strength, and function following maximal muscle stress. This controlled clinical trial explores accessible recovery methods to optimize physiological adaptation and reduce fatigue from high-intensity training. Forty men and forty women will be randomly assigned to one of four groups: BFR at 80% of total occlusion pressure, BFR at 60% of total occlusion pressure, BFR at 10 mmHg pressure, or a control group resting without BFR. Each participant will complete initial assessments, undergo a muscle stress protocol, then receive their assigned intervention continuously for 20 minutes. Follow-up assessments will occur immediately, and then at 24, 48, and 72 hours after exercise. Participants will be evaluated on muscle pain using a Numerical Rating Scale, recovery and discomfort via Likert scales, exertion with the Borg scale, and muscle cellular integrity using bioelectrical impedance analysis. Muscle tone, stiffness, elasticity, strength, and power will also be measured with specialized devices and functional tests. The study includes monitoring for safety and consent procedures, and all data will be handled confidentially over the course of the trial.
CONDITIONS
Brief Title
Effect of Blood Flow Restriction on Recovery After Maximal Resistance Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 35 years
- Ability to perform vigorous physical activities
- Healthy men and women without diabetes, hypertension, or inflammatory, psychiatric, cardiovascular, or respiratory diseases
- No predisposing risk factors for thromboembolism
You will not qualify if you...
- Presence of any health problem preventing continued participation
- Desire to withdraw from the study
- Use of medications, electrotherapy, or other treatments during the study that may affect results
- Refusal to sign the informed consent form
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo initial assessments including pain, perception of recovery and discomfort, perception of effort, cellular integrity, muscle tone, stiffness, elasticity, muscle strength, and functional muscle power tests.
1 visit (in-person)
Duration - 1 day
Participants perform a muscle stress protocol followed by the assigned intervention: blood flow restriction with 80% or 60% occlusion, 10 mmHg occlusion pressure, or rest without BFR for 20 minutes.
1 visit (in-person)
Duration - 3 days
Participants complete assessments immediately, and at 24, 48, and 72 hours after exercise measuring pain, perception of recovery, perception of effort, cellular integrity, muscle tone, muscle strength, and muscle power.
4 visits (in-person)
Trial Site Locations
Total: 1 location
1
Franciele Marques Vanderlei
Presidente Prudente, São Paulo, Brazil, 19060-900
Actively Recruiting
Research Team
F
Franciele Marques Vanderlei PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
4
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