Actively Recruiting
Comparing Hot-Water Baths Before or After Muscle-Lengthening Exercise on Muscle Recovery and HSP70 Levels in Healthy Young Male Athletes Aged 19 to 25
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-04-30
96
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying how hot-water immersion before or after muscle-lengthening exercise affects muscle function and the expression of heat shock protein 70 HSP70 in healthy young athletes. Muscle lengthening causes responses such as strength loss, soreness, immune activity, and increased HSPs, which help protect and repair cells. Combining heat and exercise may enhance these protective responses, but the best timing for heat application is still unknown. Participants will be randomly assigned to one of three groups hot-water immersion at 41C 24 hours before exercise, hot-water immersion at 41C immediately after exercise, or a sham immersion at 36C after exercise. Immersion sessions last 40 minutes aiming to raise core temperature above 38.5C for heat stress groups. The study also uses devices like a dynamometer, pressure algometer, and others to assess muscle and physiological responses. During the study, participants will undergo assessments of muscle function and HSP70 concentration over one year. Researchers will monitor core and muscle temperatures and use various tools to measure recovery and physiological changes. The study involves healthy athletic men aged 19 to 25 and includes safety monitoring to track effects over time until the study ends in February 2027.
CONDITIONS
Brief Title
Effects of Hot Baths Prior or After a Damaging Protocol on Muscle Function and HSP70 Expression
Research Team
Y
Yannis Hamidou, MD
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