The Effect of Clip-traction on ESD Resection Time. A Randomized Controlled Trial

What this Trial Is About

This research aims to evaluate the effect of using a clip-traction device during endoscopic submucosal dissection (ESD) for patients with adenomas or early colorectal cancer in the colon or rectum. The study compares the use of a traction device against the standard ESD method to see if it impacts the speed of tissue removal. Patients will be randomized into groups to receive either the clip-traction device or the standard procedure. The clip-traction device involves attaching an endoscopic clip with a loop of dental floss to the lesion, which is then anchored to the adjacent bowel wall by another clip to provide tension for easier dissection. One group will undergo the standard ESD without this device, while the other group will have the device used mandatorily. The location, size, and shape of the lesion will be recorded during the procedure. Participants will be monitored during the procedure with the time measured precisely using a stopwatch to assess resection speed in square millimeters per minute. The study tracks these times to compare efficiency between the two methods. The trial is randomized, unblinded, and sponsored by the Karolinska Institutet. The study involves adults aged 18 to 95 years who meet the criteria and excludes those with dementia or inability to understand study information.

The Effect of Clip-traction on ESD Resection Time.