Actively Recruiting

Age: 18Years +
All Genders
NCT06844448

The Effect of Different Risk Factors on the Success Rate of VPT

Led by Semmelweis University · Updated on 2025-03-06

400

Participants Needed

1

Research Sites

313 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure. It explores the success rates of these treatments compared and investigates co-factors influencing these rates, including age. This prospective cohort study involves patients over 18 with restorable teeth and exposed pulp chambers. Success is measured through clinical and radiological criteria over a follow-up period of up to four years. The study also aims to identify if there's an age threshold affecting the preference for VPT over root canal therapy.

CONDITIONS

Official Title

The Effect of Different Risk Factors on the Success Rate of VPT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age who have at least one tooth with a pulp chamber that has been opened during a dental procedure or is likely to be opened during restoration of the tooth
  • The tooth is responsive to a sensitivity test with cold spray
  • The coronal part must be restorable
  • The periodontal depth around the tooth should be 0 according to the Dental Practicality Index Periodontal Treatment Need, i.e. the probing depth around the tooth should not be greater than 3.5 mm
Not Eligible

You will not qualify if you...

  • Internal or external resorption in the tooth
  • Root development of the tooth is not complete or the tooth is a deciduous tooth
  • Absolute isolation cannot be performed during the procedure
  • No pulp exposure occurs after complete removal of caries
  • The crown of the tooth cannot be restored
  • Periodontium surrounding tooth affected by moderate or severe marginal periodontitis (probing depth deeper than 3.5 mm)
  • Pulp exposure due to traumatic injury
  • Baseline radiograph shows signs of severe pulp calcification
  • Periapical lesion is present around the root (Periapical index of the tooth greater than 2)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Department for Restorative Dentistry and Endodontics, Semmelweis University

Budapest, Hungary, 1088

Actively Recruiting

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Research Team

M

Melinda Zs Polyák, DMD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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