Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT07320846

The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis

Led by Saglik Bilimleri Universitesi · Updated on 2026-01-06

39

Participants Needed

1

Research Sites

94 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The main questions it aims to answer are: * Does respiratory muscle strengthening exercise added to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have additional benefits on rehabilitation outcome measures such as exercise capacity, shortness of breath, and muscle strength? * Does the gain obtained with respiratory muscle strengthening iin patients with rheumatoid arthritis-associated interstitial lung disease increase the quality of life of patients and have a positive effect on their psychological state? * Does respiratory rehabilitation applied to iin patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Does respiratory muscle strengthening training applied in addition to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Participants will be included in two different respiratory rehabilitation programs with and without respiratory muscle training, and pre- and post- treatment rehabilitation criteria and genetic changes will be compared.

CONDITIONS

Official Title

The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with rheumatoid arthritis according to ACR/EULAR 2010 criteria
  • Diagnosis duration longer than 2 years
  • Disease activity score (DAS28) below 5.1
  • Voluntary participation in the study
  • Presence of lung involvement related to rheumatoid arthritis
Not Eligible

You will not qualify if you...

  • Orthopedic deformities that could affect treatment
  • Pregnancy
  • Uncontrolled diabetes or heart disease
  • Participation in a rehabilitation program within the last 6 months
  • Body mass index over 30
  • Severe organ failure
  • Recent acute coronary syndrome
  • Active infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Health Sciences

Istanbul, Turkey, Turkey (Türkiye)

Actively Recruiting

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Research Team

Z

Zeynep Betül ÖZCAN

CONTACT

E

Esra PEHLİVAN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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