Actively Recruiting
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis
Led by Saglik Bilimleri Universitesi · Updated on 2026-01-06
39
Participants Needed
1
Research Sites
94 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The main questions it aims to answer are: * Does respiratory muscle strengthening exercise added to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have additional benefits on rehabilitation outcome measures such as exercise capacity, shortness of breath, and muscle strength? * Does the gain obtained with respiratory muscle strengthening iin patients with rheumatoid arthritis-associated interstitial lung disease increase the quality of life of patients and have a positive effect on their psychological state? * Does respiratory rehabilitation applied to iin patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Does respiratory muscle strengthening training applied in addition to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Participants will be included in two different respiratory rehabilitation programs with and without respiratory muscle training, and pre- and post- treatment rehabilitation criteria and genetic changes will be compared.
CONDITIONS
Official Title
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with rheumatoid arthritis according to ACR/EULAR 2010 criteria
- Diagnosis duration longer than 2 years
- Disease activity score (DAS28) below 5.1
- Voluntary participation in the study
- Presence of lung involvement related to rheumatoid arthritis
You will not qualify if you...
- Orthopedic deformities that could affect treatment
- Pregnancy
- Uncontrolled diabetes or heart disease
- Participation in a rehabilitation program within the last 6 months
- Body mass index over 30
- Severe organ failure
- Recent acute coronary syndrome
- Active infection
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Health Sciences
Istanbul, Turkey, Turkey (Türkiye)
Actively Recruiting
Research Team
Z
Zeynep Betül ÖZCAN
CONTACT
E
Esra PEHLİVAN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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