Observational Study on Risk Factors and Outcomes in Progressive Pulmonary Fibrosis Among Adults with Interstitial Lung Disease

What this Trial Is About

This research aims to understand the risk factors, prevalence, and mortality associated with progressive pulmonary fibrosis PPF in patients who have interstitial lung disease ILD with pulmonary fibrosis visible on scans, excluding those with idiopathic pulmonary fibrosis IPF. It focuses on identifying connections between patient characteristics and progression of the disease over time. Participants will have initial assessments including collection of personal and medical histories, blood samples, detailed lung imaging high resolution computed tomography, lung function tests, and a 6-minute walk test. These evaluations will be repeated at 6 and 12 months, with additional blood samples and tests to monitor disease progression. Throughout the study, researchers will track lung function, exercise capacity, blood markers, and imaging results to measure disease progression and outcomes. The main goal is to link factors like age, gender, body mass index, and lung physiology scores to PPF progression over one year. The study extends up to 36 months to observe disease prevalence and long-term outcomes.

A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis