Actively Recruiting

Age: 16Years +
FEMALE
ID07252687

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men (TRANSBREAST) - a Prospective Cohort Study

Led by Medical University Innsbruck · Updated on 2026-03-06

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to examine the psychological and physical effects of breast development in transmasculine or genderdiverse individuals assigned female at birth who experience breast dysphoria. The study focuses on how gender-affirming hormone therapy (GAHT) and mastectomy impact this form of distress, which is related to depression, anxiety, and suicidality. It also explores how different coping strategies, such as binding or taping, influence well-being. Participants will complete quality of life and chest dysphoria questionnaires at multiple times: before starting hormone therapy, three months after starting hormone therapy, after breast-affirming surgery, and up to two years following initial enrollment. This observational study follows individuals through these stages to systematically assess changes over time. Throughout the study, participants' responses on the Chest Dysphoria Measure and iTransQoL questionnaires will be collected and analyzed. The primary outcome is the Chest Dysphoria Measure Score assessed from enrollment through two years after. The study is designed to understand the effects of gender-affirmative treatments on breast perception and mental health in this population.

CONDITIONS

Brief Title

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men

Who Can Participate

Age: 16Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Assigned female at birth
  • Have not started gender-affirming hormone therapy (GAHT)
  • Have not had a mastectomy
  • Able to give informed consent
  • Understand German language sufficiently
Not Eligible

You will not qualify if you...

  • Currently undergoing gender-affirming hormone therapy
  • Mastectomy already performed
  • Lacking capacity to provide consent
  • Insufficient German language skills to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 2 years

Participants complete questionnaires to assess chest dysphoria and quality of life before starting hormone therapy, 3 months after starting hormone therapy, after breast-affirming surgery, and up to two years after enrollment.

4 questionnaire time points

Trial Site Locations

Total: 1 location

1

Medical University Innsbruck

Innsbruck, Austria

Actively Recruiting

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Research Team

K

Katharina Feil

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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