Impact of Gender-Affirming Hormone Therapy and Mastectomy on Breast Perception in Trans Men and Gender Diverse Individuals

What this Trial Is About

This research aims to examine the psychological and physical effects of breast development in transmasculine or genderdiverse individuals assigned female at birth who experience breast dysphoria. The study focuses on how gender-affirming hormone therapy GAHT and mastectomy impact this form of distress, which is related to depression, anxiety, and suicidality. It also explores how different coping strategies, such as binding or taping, influence well-being. Participants will complete quality of life and chest dysphoria questionnaires at multiple times before starting hormone therapy, three months after starting hormone therapy, after breast-affirming surgery, and up to two years following initial enrollment. This observational study follows individuals through these stages to systematically assess changes over time. Throughout the study, participants responses on the Chest Dysphoria Measure and iTransQoL questionnaires will be collected and analyzed. The primary outcome is the Chest Dysphoria Measure Score assessed from enrollment through two years after. The study is designed to understand the effects of gender-affirmative treatments on breast perception and mental health in this population.

The Effect of Gender-affirmative Measures on Breast Perception in Trans Men