Effect of Hypothermia on the Correlation Between Bispectral Index (BIS) and Patient State Index (PSI) During Cardiopulmonary Bypass

What this Trial Is About

Researchers are evaluating how hypothermia affects the relationship between two brain monitoring indices, the Bispectral Index (BIS) and Patient State Index (PSI), during cardiac surgery involving cardiopulmonary bypass in adult patients. This observational study focuses on whether the correlation between these indices changes between normal body temperature and lowered body temperature phases, and how they respond as temperature decreases. The study aims to clarify the impact of hypothermia on brain activity monitoring during surgery, which may influence anesthetic management. Adult patients undergoing elective on-pump coronary artery bypass surgery will receive standard general anesthesia and surgical care. BIS and PSI sensors will be applied before anesthesia induction, and both indices will be monitored simultaneously during surgery. Data will be recorded at specific time points representing normothermic, hypothermic, and rewarming phases of cardiopulmonary bypass, without altering routine clinical management. Participants will be monitored continuously with BIS and PSI devices during surgery, with data collection focused on temperature-based phases of cardiopulmonary bypass. Researchers will analyze the difference in correlation between BIS and PSI at normal and lowered temperatures, changes per degree Celsius during cooling and rewarming, and agreement in clinical depth-of-anesthesia categories. The study involves only intraoperative monitoring and assessment during the surgery period.

Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass