Studying the Impact of Nasogastric Tube Use on Complications in Adults with Small Bowel Obstruction

What this Trial Is About

Small bowel obstruction SBO is a surgical emergency where normal bowel movements are blocked, leading many patients to visit emergency departments annually. Most patients with SBO are initially managed without surgery, often using a nasogastric tube NGT to relieve gastric pressure and reduce complications. However, the true benefit of NGT placement for preventing respiratory complications is unclear, with some observational data suggesting it may increase pneumonia risk. This study is a randomized, controlled, open-label trial comparing two groups of patients with SBO who are planned for non-operative management. One group will receive a nasogastric tube placement, while the other will have the tube deferred. Both groups will receive other care according to local guidelines and will be monitored until their SBO resolves either spontaneously or through surgery. A total of 1000 patients will be enrolled across multiple centers. Participants will be regularly monitored for lung-related complications and whether they require care in a high dependency or intensive care unit during the hospital stay or up to 30 days. Other outcomes include surgery rates, death within one year, time to functional recovery, bowel complications, hospital stay length, and readmission rates. The study includes long-term follow-up for one year and qualitative interviews to assess health-economic impacts. This trial aims to provide high-quality evidence on the role of nasogastric tubes in managing SBO.

The Effect of Nasogastric Tube Placement on Complications in Patients With Small Bowel Obstruction - the SBO-TUBE Trial