Actively Recruiting

Age: 18Years - 50Years
FEMALE
Healthy Volunteers
NCT05753124

Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes

Led by Chelsea and Westminster NHS Foundation Trust · Updated on 2023-03-03

700

Participants Needed

1

Research Sites

648 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight/obese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery. The aims of the study are to investigate the maternal and fetal/neonatal, biophysical and biochemical, intra-uterine environment and postnatal profile of pregnancies: 1. affected by maternal obesity and/or GDM/T2DM compared to pregnancies with normal maternal body mass index (BMI). 2. with previous maternal bariatric surgery compared to pregnancies without previous bariatric surgery but matched for maternal pre-surgery and early pregnancy BMI.

CONDITIONS

Official Title

Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes

Who Can Participate

Age: 18Years - 50Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with a normal BMI (less than 30)
  • Pregnant women with obesity (BMI 30 or higher)
  • Pregnant women with glucose disorders such as gestational or type 2 diabetes
  • Pregnant women who have had previous bariatric surgery
Not Eligible

You will not qualify if you...

  • Pregnant women under 18 years of age
  • Pregnant women carrying twins or triplets

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chelsea & Westminster Hospital Nhs Ft

London, United Kingdom

Actively Recruiting

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Research Team

D

DAMON FOSTER

CONTACT

D

DORIS DABY

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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