Actively Recruiting

Phase Not Applicable
Age: 21Years - 35Years
All Genders
Healthy Volunteers
NCT07165808

Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches

Led by Emory University · Updated on 2026-02-27

84

Participants Needed

1

Research Sites

98 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to assess the effects of nicotine concentration and its interplay with pH on sensory experience, product appeal, and abuse liability of NPs among young adults NP users. Primary objective is to assess the effect of variation in nicotine concentration in nicotine pouches (NPs) and its interaction effect with pH level on three proximal outcomes of relevance to regulation: (1) sensory experience, (2) product appeal, and (3) abuse liability of NPs.

CONDITIONS

Official Title

Effect of Product Characteristics on the Abuse Liability of Nicotine Pouches

Who Can Participate

Age: 21Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Current established users of nicotine pouches who have used them in the past 30 days and currently use every day or some days
  • Positive cotinine test via saliva test strip
  • Unmotivated to quit nicotine use
  • Able to read and speak English
  • Poly-users of nicotine pouches, e-cigarettes (vaping at least 20 days per month), and tobacco (smoking at least 4 cigarettes per day for 2 or more years) are eligible
Not Eligible

You will not qualify if you...

  • Planning to cut down or quit using nicotine in the next 30 days
  • Currently pregnant or breastfeeding
  • History of stroke, seizures, high blood pressure, heart disease, or cardiovascular disease contraindications for nicotine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rollins School of Public Health

Atlanta, Georgia, United States, 30322

Actively Recruiting

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Research Team

D

Dae Hee Han, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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