Actively Recruiting
Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
Led by University of Cyprus · Updated on 2024-06-25
200
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets. The project will involve drug repurposing using Mendelian Randomization, a smoking cessation intervention, and the analysis of methylation status in participants undergoing nicotine withdrawal.
CONDITIONS
Official Title
Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-60 years old
- Current daily cigarette smoker
- Able to understand study procedures and provide informed consent
- For females, non-pregnant and non-lactating
You will not qualify if you...
- Significant uncontrolled medical conditions (e.g. cardiovascular disease, respiratory disorders, cancer) that could affect smoking behavior or study participation
- Major uncontrolled psychiatric disorders (e.g. schizophrenia, bipolar disorder, severe depression)
- Current substance use disorder (except nicotine dependence)
- Taking medications that could significantly interfere with study objectives (e.g. medications for smoking cessation)
- Significant cognitive impairment that prevents completion of study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Center for Applied Neuroscience (CAN)
Nicosia, Cyprus, 2100
Actively Recruiting
Research Team
A
Andrea N Georgiou, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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