Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT07554105

Effect of Transcranial Random Noise Stimulation on the Performance in Language Tasks

Led by Adrian Guggisberg · Updated on 2026-04-28

90

Participants Needed

1

Research Sites

93 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Language is an essential part of daily life, enabling us to communicate, understand others, read, and learn. Certain brain injuries can disrupt these abilities, and current treatments do not always lead to a full recovery. To improve future therapeutic approaches, it is necessary to better understand how the brain processes language and how its activity can be modulated. This study aims to evaluate the effects of a non-invasive brain stimulation technique called transcranial random noise stimulation. This method involves applying a very weak electrical current to the scalp to modulate the activity of brain regions involved in language. It is commonly used in research and is considered safe when administered in accordance with current guidelines. Healthy adult volunteers will participate in this study. Each participant will take part in two sessions spaced about a week apart. During one session, active stimulation will be used, and during the other, placebo stimulation will be used. Placebo stimulation resembles the actual stimulation but has no active effect. Neither the participants nor the researchers will know which type of stimulation is being used during each session. During the sessions, participants will perform various language tasks, and their brain activity will be recorded using an electroencephalogram (EEG), a painless method. This study does not provide any direct benefit to participants. The risks are low and limited to temporary sensations, such as a tingling sensation on the scalp. The results will provide a better understanding of how the brain processes language and could eventually contribute to the development of new rehabilitation approaches.

CONDITIONS

Official Title

Effect of Transcranial Random Noise Stimulation on the Performance in Language Tasks

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 35 years or between 60 and 90 years
  • Native French speaker
  • Right handed
  • Willing and able to provide informed consent
  • Normal or corrected-to-normal vision and hearing
Not Eligible

You will not qualify if you...

  • History of neurological or psychiatric disease
  • Regular use of benzodiazepines, neuroleptics, or psychoactive drugs
  • Major language deficit, developmental language disorder, arthropathies, or other mechanical language impairments
  • Inability to understand or follow study procedures
  • Contraindications to brain stimulation, including:
    • History of epilepsy or severe migraine
    • Pacemaker or other active implants
    • Metallic objects in the head
    • Skull breach such as craniotomy
    • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Division of Neurorehabilitation, University Hospital of Geneva

Geneva, Canton of Geneva, Switzerland, 1211

Actively Recruiting

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Research Team

A

Adrian Guggisberg, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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