Actively Recruiting
Effect of Transcranial Random Noise Stimulation on the Performance in Language Tasks
Led by Adrian Guggisberg · Updated on 2026-04-28
90
Participants Needed
1
Research Sites
93 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Language is an essential part of daily life, enabling us to communicate, understand others, read, and learn. Certain brain injuries can disrupt these abilities, and current treatments do not always lead to a full recovery. To improve future therapeutic approaches, it is necessary to better understand how the brain processes language and how its activity can be modulated. This study aims to evaluate the effects of a non-invasive brain stimulation technique called transcranial random noise stimulation. This method involves applying a very weak electrical current to the scalp to modulate the activity of brain regions involved in language. It is commonly used in research and is considered safe when administered in accordance with current guidelines. Healthy adult volunteers will participate in this study. Each participant will take part in two sessions spaced about a week apart. During one session, active stimulation will be used, and during the other, placebo stimulation will be used. Placebo stimulation resembles the actual stimulation but has no active effect. Neither the participants nor the researchers will know which type of stimulation is being used during each session. During the sessions, participants will perform various language tasks, and their brain activity will be recorded using an electroencephalogram (EEG), a painless method. This study does not provide any direct benefit to participants. The risks are low and limited to temporary sensations, such as a tingling sensation on the scalp. The results will provide a better understanding of how the brain processes language and could eventually contribute to the development of new rehabilitation approaches.
CONDITIONS
Official Title
Effect of Transcranial Random Noise Stimulation on the Performance in Language Tasks
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 35 years or between 60 and 90 years
- Native French speaker
- Right handed
- Willing and able to provide informed consent
- Normal or corrected-to-normal vision and hearing
You will not qualify if you...
- History of neurological or psychiatric disease
- Regular use of benzodiazepines, neuroleptics, or psychoactive drugs
- Major language deficit, developmental language disorder, arthropathies, or other mechanical language impairments
- Inability to understand or follow study procedures
- Contraindications to brain stimulation, including:
- History of epilepsy or severe migraine
- Pacemaker or other active implants
- Metallic objects in the head
- Skull breach such as craniotomy
- Pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Division of Neurorehabilitation, University Hospital of Geneva
Geneva, Canton of Geneva, Switzerland, 1211
Actively Recruiting
Research Team
A
Adrian Guggisberg, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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