Actively Recruiting
Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease
Led by International Vaccine Institute · Updated on 2026-02-18
10000
Participants Needed
1
Research Sites
66 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this observational study is to learn about the impact of malaria vaccination on the risk of invasive non-typhoidal Salmonella disease in children below the age of 5. Eligible participants residing in the Kisantu Health Zone (DRC) and presenting fever are enrolled in healthcare facilities and tested for malaria and iNTS. Using a case-control (test-negative) design, the researchers will look at the malaria vaccination status of participants with and without iNTS infection to determine if the malaria vaccine protects against iNTS.
CONDITIONS
Official Title
Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of all ages currently living in the catchment area of the health center presenting to healthcare facility with objective fever of at least 38.0 0C tympanic or 37.5 0C axillary
- Patients of all ages currently living in the catchment area of the health center presenting to healthcare facility with reported fever 53 consecutive days within 7 days of presentation
You will not qualify if you...
- None specified
AI-Screening
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Trial Site Locations
Total: 1 location
1
Institut National de Recherche Biomedicale (INRB)
Kinshasa, Democratic Republic of the Congo
Actively Recruiting
Research Team
B
Birkneh Tadesse, MD, PHD
CONTACT
C
Camille Dauvergne, PharmD, M.S.c
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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