Actively Recruiting
The Effects of the CF Carrier State on the Kidneys and Pancreas
Led by Philip Polgreen · Updated on 2026-01-07
1250
Participants Needed
1
Research Sites
236 weeks
Total Duration
On this page
Sponsors
P
Philip Polgreen
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.
CONDITIONS
Official Title
The Effects of the CF Carrier State on the Kidneys and Pancreas
Who Can Participate
Eligibility Criteria
You may qualify if you...
- CF carriers identified through genetic testing
- Controls with no previous CF carrier test results
- Age between 18 and 100 years
- Ability to provide written informed consent
- Ability to speak English
You will not qualify if you...
- Diagnosed with cystic fibrosis (CF)
- Unable to speak English
- Currently pregnant
- Unable to provide written informed consent
- Prisoner status
- Currently taking any medications for diabetes treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
Actively Recruiting
Research Team
P
Philip M Polgreen, MD
CONTACT
S
Shelby L Francis, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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