Guided Internet-delivered Treatment for Moderate Depression, Social Anxiety Disorder and Panic Disorder - An Open Naturalistic Multicentre Cost-effectiveness Trial

What this Trial Is About

Researchers are evaluating the effectiveness and cost-effectiveness of a therapist-guided internet-based cognitive behavioral therapy (ICBT) program called eMeistring. This program targets adults with moderate depression, social anxiety disorder, and panic disorder in routine healthcare settings. The study aims to understand who benefits from the treatment, predictors of drop-out, and how user experience affects adherence and outcomes across multiple clinics. Participants receive up to nine guided ICBT sessions delivered online, with weekly therapist support via secure email. The treatment starts with an initial face-to-face visit, followed by the online modules, and concludes with a final face-to-face session. Therapists involved are licensed healthcare professionals such as psychologists and social workers. The program is integrated as standard care at four hospital locations, and patients enter through usual clinical pathways. During the study, participants complete questionnaires on symptom severity, quality of life, work and social function, medication use, and satisfaction at several points: before treatment, up to 14 weeks after starting, six months later, and after two years. Routine clinical follow-up monitors any adverse events, including suicidal behavior alerts. Researchers will analyze effectiveness, adherence, drop-out predictors, and cost-effectiveness across clinics and patient groups over the study period.

Effects and Cost-effectiveness of e-Meistring - a Guided Internet-delivered Psychological Treatment