Actively Recruiting
Aging, Beta Blockers, and Thermoregulatory Responses
Led by University of Texas Southwestern Medical Center · Updated on 2025-10-23
22
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
CONDITIONS
Official Title
Aging, Beta Blockers, and Thermoregulatory Responses
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy and free of any significant medical problems
- Normal resting electrocardiogram
- 65+ years of age
- Controlled cholesterol of less than 200 mg/dl
- Controlled blood pressure of less than 140/90 mmHg
You will not qualify if you...
- Known diseases or chronic conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, uncontrolled hypertension, and uncontrolled hypercholesterolemia
- Serious abnormalities detected on routine screening
- Taking prescribed or over-the-counter medications that affect cardiac function or sweating
- Current smokers or individuals who smoked regularly within the past 3 years
- Body mass index of 31 kg/m2 or higher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IEEM Texas Health Presbyterian Hospital Dallas
Dallas, Texas, United States, 75231
Actively Recruiting
Research Team
E
Erin Harper, MS
CONTACT
C
Courtney Kirby, RN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
6
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