Effects of MediDrink Platinum+ and Fava Bean Protein Hydrolysate on Fitness in Older Adults with Sarcopenia A Randomized Study of Protein Supplementation

What this Trial Is About

Researchers are investigating the effects of MediDrink Platinum+, which contains a novel protein blend called SPR-01, alone or combined with PeptiStrong, a fava bean protein hydrolysate, on general fitness in older adults aged 60 and above who are malnourished and have sarcopenia. This multicenter, randomized study aims to measure improvements in physical function and overall well-being in this population using tools like the Barthel Index. Additional outcomes include hand grip strength, physical performance tests, and changes in fat-free body mass. The study uses a "Y" design where all 75 participants first consume a base formula (MediDrink Platinum) for 2 weeks. After this, they are randomly assigned to one of two groups for 10 weeks: one group receives SPR-01 alone at a personalized dose providing at least 1200 kcal/day, while the other group receives SPR-01 plus PeptiStrong at a dose of at least 1200 kcal/day and 2.4 g/day, respectively. This design allows comparison of the effects of the protein blend with and without the additional supplement. During the study, participants will be assessed on general well-being and fitness, mainly through the Barthel Index over weeks 0 to 12. Other measures include tests of muscle strength and physical function. Participants need to be able to eat orally, walk independently, and complete health questionnaires. The study monitors safety and treatment effects throughout the 12-week period.

The Effects of MediDrink Platinum+ and Fava Bean Protein Hydrolysate on Fitness in an Aged Population