Actively Recruiting
C-Protein in Fatigue and Aging
Led by University of Oregon · Updated on 2025-05-07
24
Participants Needed
1
Research Sites
477 weeks
Total Duration
On this page
Sponsors
U
University of Oregon
Lead Sponsor
W
Wu Tsai Human Performance Alliance
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
CONDITIONS
Official Title
C-Protein in Fatigue and Aging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults between the ages 18-35 or 65-80 years
- Healthy by self-report
- Willing to participate in all aspects of the study design including muscle biopsy, unilateral exercise, and physical activity monitoring
- Fluent in English (due to lack of translation services)
You will not qualify if you...
- Orthopaedic limitation (severe knee osteoarthritis, prior joint replacement, etc.)
- Dementia or related mental issues posing risk
- Known untreated endocrine disease (hypo/hyper thyroidism, Addison's Disease, Cushing's syndrome, etc.)
- Untreated or poorly-controlled hypertension (stage 2, >140/90 mmHg)
- Significant heart, liver, kidney, or respiratory disease
- Diabetes (insulin dependent or non-insulin dependent)
- Known coagulopathies
- Use of anabolic steroids within prior six months
- Cancer treatment except successful Mohs Surgery for skin cancers
- Unexpected weight loss >5 kg in last 12 months
- Active smoker or quit within the last year
- Current alcohol or drug use disorder as defined by binge drinking or excess consumption
- Diagnosed neuromuscular disorder
- Allergy to lidocaine
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Oregon
Eugene, Oregon, United States, 97403
Actively Recruiting
Research Team
D
Damien M Callahan, Ph.D.
CONTACT
K
Karen Wiedenfeld Needham, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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