Actively Recruiting

Phase Not Applicable
Age: 20Years - 35Years
FEMALE
Healthy Volunteers
NCT05119868

Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring

Led by Federico II University · Updated on 2026-02-12

276

Participants Needed

2

Research Sites

227 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Allergy prevalence is increasing steadily with some describing as the "epidemic of the twenty-first century". Maternal diet during pregnancy has been linked to offspring allergy risk, so it represents a potential target for allergy prevention. The Mediterranean Diet (MD) is considered one of the healthiest dietary models which exerts regulatory effects on immune system, due to the synergistic and interactive combinations of nutrients. We aim to study the effects of MD in pregnancy on the onset of allergic diseases at 2 years of age in the offspring.

CONDITIONS

Official Title

Effects of the Mediterranean Diet During Pregnancy on the Onset of Allergies in the Offspring

Who Can Participate

Age: 20Years - 35Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy women aged 20 to 35 years
  • Currently in the first trimester of pregnancy
  • At risk of having a baby with atopy
Not Eligible

You will not qualify if you...

  • Presence of infections
  • Presence of malignancies
  • Major gastrointestinal malformations
  • Immunodeficiencies
  • Autoimmune diseases
  • Chronic inflammatory bowel diseases
  • Functional gastrointestinal disorders
  • Celiac disease
  • History of abdominal surgery with gastrointestinal resection
  • Neuropsychiatric disorders
  • Central nervous system disorders
  • Following a vegan diet
  • Twin pregnancy
  • Genetic disorders
  • Metabolic disorders

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Department of Traslational Medical Science - University of Naples Federico II

Naples, Italy, 80131

Actively Recruiting

2

Department of Traslational Medical Science

Naples, Italy, 80131

Not Yet Recruiting

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Research Team

R

Roberto Berni Canani

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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