Menarche, pubertal timing and the brain: female-specific patterns of brain maturation beyond age-related development.
Nina Gottschewsky, Dominik Kraft, Tobias Kaufmann
https://pubmed.ncbi.nlm.nih.gov/38532493Actively Recruiting
Led by Riphah International University · Updated on 2026-05-08
46
Participants Needed
1
Research Sites
4 weeks
Total Duration
Researchers are evaluating the effects of two manual therapy techniques, sacral release technique and lumbar mobilization, on pain, symptom severity, and quality of life in adolescent females with primary dysmenorrhea. This randomized clinical trial involves 46 females aged 13 to 19 years diagnosed with primary dysmenorrhea. The study aims to compare how each technique impacts these outcomes over a period of six weeks. Participants are randomly assigned to one of two groups. Group A receives the sacral release technique, where gentle, sustained holds lasting 3 to 5 minutes are applied 2 to 3 times per session, with sessions lasting 15 to 20 minutes, three times per week for two consecutive menstrual cycles. Group B undergoes lumbar mobilization treatments three times per menstrual cycle over the same six-week period. Both interventions are provided over two menstrual cycles. During the study, pain intensity will be measured using the Numerical Pain Rating Scale, symptom severity will be assessed with a menstrual symptom questionnaire, and quality of life will be evaluated using the EuroQOL-5 Dimension Questionnaire. These assessments occur at the end of the six-week intervention period. Data will be analyzed to determine statistical significance. Participants will attend sessions and be monitored for changes in pain, symptoms, and quality of life throughout the study.
CONDITIONS
Effects of Sacral Release Technique and Lumbar Mobilization in Primary Dysmenorrhea.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants receive either Sacral Release Technique or Lumbar Mobilization therapy to relieve pain and improve symptoms of primary dysmenorrhea.
3 sessions per menstrual cycle for two consecutive cycles
Total: 1 location
1
Ittefaq Hospital
Lahore, Punjab Province, Pakistan, 6400
Actively Recruiting
I
imran G amjad
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Nina Gottschewsky, Dominik Kraft, Tobias Kaufmann
https://pubmed.ncbi.nlm.nih.gov/38532493Xueyan Wu, Du Zhen, Xiaotian Liu...
https://pubmed.ncbi.nlm.nih.gov/37549686