Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
Healthy Volunteers
NCT07037511

Effects of Salbutamol in Athletes and Implications for Screening and Sports

Led by University of British Columbia · Updated on 2026-03-13

64

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.

CONDITIONS

Official Title

Effects of Salbutamol in Athletes and Implications for Screening and Sports

Who Can Participate

Age: 18Years - 55Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aerobic capacity (V̇O2max) greater than 120% predicted
  • Body mass index (BMI) > 18 and < 30 kg/m2
  • Ability to read and understand English
  • Currently training and/or competing in endurance sports (i.e. running or cycling)
Not Eligible

You will not qualify if you...

  • Current smoking or smoking history as defined by more than 1 pack year for cigarettes or equivalent cannabis use
  • Cannabis use within the past 30 days
  • Use of vaping devices or e-cigarettes within the past 30 days or more than 10 times lifetime
  • History or current symptoms of cardiopulmonary disease (excluding controlled asthma)
  • Contraindications to exercise testing preventing safe exercise
  • Neuromuscular or musculoskeletal condition

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

St. Paul's Hospital

Vancouver, British Columbia, Canada, V6Z1Y6

Actively Recruiting

Loading map...

Research Team

S

Satvir S Dhillon, MSc

CONTACT

J

Jordan A Guenette, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here