Actively Recruiting

Age: 18Years +
All Genders
ID05942729

Etiological Diagnosis of Cardiac Diseases Based on Echocardiographic Images and Clinical Data

Led by Hospices Civils de Lyon · Updated on 2023-07-13

1000

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how advanced analysis of echocardiogram images combined with patient data can help diagnose the causes of certain heart diseases. This study focuses on building accurate and explainable artificial intelligence (AI) models to predict the origin of cardiac conditions, particularly hypokinetic cardiomyopathy and left ventricular hypertrophy, using echocardiographic information. The goal is to develop digital tools that improve understanding and diagnosis of heart disease causes. The study includes two groups of patients: one with hypokinetic cardiomyopathy where heart function is reduced but the cause is unclear, and another with left ventricular hypertrophy, a condition where the heart muscle is thickened due to various potential causes. Researchers will use echocardiographic data and patient clinical information collected during routine care, such as cardiac CT, MRI, or coronary angiography, to train and test AI algorithms. These algorithms will learn from 80% of the collected data and be evaluated on the remaining 20%. Participants will provide echocardiogram images of sufficient quality for analysis. The researchers will compare AI-based diagnoses with those made by physicians using additional tests to evaluate AI accuracy. The main measure is how well the AI predicts the cause of heart disease compared to standard medical diagnosis. The study does not involve treatment changes and will continue until 2027, with participants contributing data for AI development and validation.

CONDITIONS

Brief Title

Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with transthoracic echocardiography with satisfactory image quality (sufficient echogenicity)
Not Eligible

You will not qualify if you...

  • Minor patients (under 18 years old)
  • Patients under curatorship or guardianship

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Baseline

Participants undergo transthoracic echocardiography and other complementary examinations performed as part of routine care to determine the etiology of their cardiac condition.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 2 years

Participants are observed as their echocardiographic data and clinical information are used to develop and evaluate an artificial intelligence method for etiological diagnosis.

Visits as part of routine care; no additional trial visits required

Trial Site Locations

Total: 1 location

1

Hopital Lyon Sud

Pierre-Bénite, France, 69310

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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