Actively Recruiting

Age: 19Years +
All Genders
ID03427996

Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice; A Multicenter, Prospective Observational Study

Led by Seung-Jung Park · Updated on 2026-01-02

500

Participants Needed

8

Research Sites

260 weeks

Total Duration

On this page

Sponsors

S

Seung-Jung Park

Lead Sponsor

C

CardioVascular Research Foundation, Korea

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness and safety of rotational atherectomy, a procedure used to treat coronary artery disease, in routine clinical practice. This multicenter, prospective observational study focuses on patients with atherosclerosis and coronary stenosis who receive this intervention, aiming to better understand its outcomes in real-world settings. Participants undergo percutaneous coronary intervention with rotational atherectomy as part of their clinical care. This study does not involve randomization or placebo control but observes the outcomes following the procedure. The study tracks patients over time to assess various outcomes related to the procedure and disease progression. Throughout the study, researchers will monitor participants for target vessel failure at one year, as well as other outcomes including death, cardiac death, myocardial infarction, revascularization procedures, stent thrombosis, stroke, and procedural success over periods extending up to five years. Follow-up visits and data collection are scheduled at multiple intervals to gather comprehensive information on safety and effectiveness. Total participation duration depends on individual follow-up schedules.

CONDITIONS

Brief Title

Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 19 years old or older
  • Patients who have received rotational atherectomy
  • Patient or guardian agrees to study protocol and follow-up schedule and provides informed written consent
Not Eligible

You will not qualify if you...

  • Life expectancy less than 1 year

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Procedure day

Participants undergo rotational atherectomy as part of routine clinical care.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 5 years

Participants are followed to assess effectiveness and safety outcomes including vessel failure, death, myocardial infarction, and revascularization up to 5 years after the procedure.

Visits at 1, 6, and 12 months, and annually at Years 3 and 5

Trial Site Locations

Total: 8 locations

1

Soon Chun Hyang University Hospital Bucheon

Bucheon-si, South Korea

Actively Recruiting

2

Daegu Catholic University Medical Center

Daegu, South Korea

Actively Recruiting

3

Chungnam National University Hospital

Daejeon, South Korea

Terminated

4

The Catholic University of Korea, Daejeon ST. Mary's Hospital

Daejeon, South Korea

Withdrawn

5

Chonnam National University Hospital

Gwangju, South Korea

Not Yet Recruiting

6

Inje University Pusan Paik Hospital

Pusan, South Korea

Terminated

7

Bundang CHA Hospital

Seongnam, South Korea

Terminated

8

Asan Medical Center

Seoul, South Korea

Actively Recruiting

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Research Team

S

Seung-jung Park, MD

J

Jung-hee Ham, RN

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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