Actively Recruiting
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
Led by Boston Children's Hospital · Updated on 2026-01-07
100
Participants Needed
1
Research Sites
235 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this proposal is to prospectively collect data from a series of 200 patients (all ages) undergoing complex cardiac surgical procedures involving cardiopulmonary bypass (CPB) to: 1. Measure the number of blood activated circulating monocytes before, during and after cardiac surgery and serum GABA and pro-inflammatory cytokine levels 2. Understand the correlation between GABA and inflammatory cytokines (and/or activated monocytes) and 3. Assess the correlation between thrombosis and monocyte activation in patients undergoing cardiac surgery under CPB and at risk of thrombosis.
CONDITIONS
Official Title
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of all ages undergoing complex cardiac surgical procedures using cardiopulmonary bypass (CPB).
You will not qualify if you...
- Patients undergoing an emergency procedure without more than one hour to review consent.
- Patients in a moribund condition classified as American Society of Anesthesiology (ASA) 5.
- Patients with hematological and/or oncological diseases.
- Jehovah's Witnesses.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
K
Koichi Yuki, MD
CONTACT
R
Rachel Bernier
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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