Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID05849025

Invasive Hemodynamic Control Cohort for The Mayo Clinic Adult Congenital Heart Disease Registry

Led by Mayo Clinic · Updated on 2026-05-05

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to provide comparative data for the Mayo Clinic Adult Congenital Heart Disease Registry by studying both healthy individuals and those with congenital heart disease. The study is observational and focuses on gathering important baseline information related to heart and lung function. Participants will be observed without receiving any specific treatment or intervention. The study involves collecting data to measure pulmonary vascular reserve at baseline, which helps researchers understand heart and lung blood flow under different conditions. During the study, participants will undergo assessments such as MRI scans and blood pressure measurements. Kidney function will be confirmed through recent lab results. Participants will be monitored for factors that might influence the heart and lung function measurements. The study is expected to continue until December 2026, with ongoing data collection at regular intervals.

CONDITIONS

Brief Title

A Study of Invasive Hemodynamic for MACHD Registry

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to give informed consent
  • Body mass index (BMI) 30 or less
  • Systolic blood pressure 140 mmHg or less
  • Diastolic blood pressure 90 mmHg or less
  • Estimated glomerular filtration rate (eGFR) above 30 within the prior 3 months
  • Able to undergo MRI scanning
Not Eligible

You will not qualify if you...

  • History of cardiovascular disease that may affect test results
  • Current orthopedic limitations
  • Currently taking any cardiac medications
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Single timepoint

Participants undergo invasive hemodynamic assessments as part of the study procedures.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 4 years

Participants are observed over time to assess pulmonary vascular reserve and related outcomes.

Trial Site Locations

Total: 1 location

1

Mayo Clinic Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

A

ACHD Research Program

A

Alexander Egbe, MBBS, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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