Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT07253038

Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

Led by Region Skane · Updated on 2026-03-11

40

Participants Needed

1

Research Sites

91 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease. Huntington disease affects motor function, psychological well-being and cognitive functions ("thinking abilities" such as paying attention, remembering and solving problems). It is also believed to affect important social functions, including the ability to understand others' intentions and emotions (social cognition). The test of interest in this study is called The Double Movie for the Assessment of Social Cognition-Multiple Choice (DMASC-MC) and will be compared to two other similar and well-known tests. The main question which the study aims to answer is: • Is DMASC-MC a useful tool for detecting problems with social functioning in adult persons with early Huntington disease? In the study, participants will meet with a medical doctor and a psychologist for assessment of different symptoms related to Huntington disease, including social functioning. Better methods for identifying problems with social functioning could help persons with Huntington disease and their families in mainly two ways. Firstly, it could increase their understanding of how the disease has affected them. Secondly, a better understanding of these problems could lead to better recommendations and interventions from medical teams, which would also benefit persons with Huntington disease and families.

CONDITIONS

Official Title

Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical diagnosis of Huntington disease
  • CAG repeat of 40 or more for HD group
  • No family history of Huntington disease or negative pre-symptomatic HD gene test for control group
  • Age between 18 and 75 years
Not Eligible

You will not qualify if you...

  • Dementia or cognitive test scores (MOCA or MMSE) less than 19
  • Other neurological disorders
  • Ongoing psychosis
  • Ongoing alcohol or drug addiction
  • Native language other than Swedish
  • Severe vision or hearing problems

AI-Screening

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Trial Site Locations

Total: 1 location

1

Skane University Hospital, Region Skane

Lund, Sweden, 22184

Actively Recruiting

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Research Team

A

Asa Petersen, MD, PhD

CONTACT

I

Isak Halling, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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