Actively Recruiting
The Social-HD Study: A Cross-Sectional Observational Study of Social Cognition in Early Huntington Disease
Led by Region Skane · Updated on 2026-03-11
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying social cognition in adults with early Huntington disease (HD), a genetic disorder affecting movement, thinking, and psychological well-being. The study aims to evaluate the usefulness of a test called the Double Movie for the Assessment of Social Cognition-Multiple Choice (DMASC-MC) in detecting social functioning problems compared to two other established tests. Better understanding social cognitive issues could help affected individuals and their families by improving awareness and guiding medical care. The study includes 20 adults with early HD and 20 healthy controls matched by age and sex. Participants undergo assessments with the DMASC-MC and two other social cognition tests: Reading the Mind in the Eyes Test and The Emotion Hexagon Test. They will also be evaluated for cognitive, psychiatric, and motor symptoms related to HD. This observational, cross-sectional study does not involve treatment but compares test results between groups. Participants meet with a medical doctor and psychologist for evaluations including cognitive tests, psychiatric assessments, and motor function exams. Researchers will measure differences in social cognition test scores between HD patients and controls and examine correlations with other clinical measures. The study seeks to improve clinical care by identifying social cognitive deficits important for planning support and communication. The total participation involves a single assessment session, with results compared at baseline.
CONDITIONS
Brief Title
Evaluation of Three Tests to Assess Social Cognition in Huntington Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of Huntington disease with CAG repeat of 40 or more for the HD group
- No heritage of Huntington disease or a negative pre-symptomatic HD gene test for the control group
- Age between 18 and 75 years
- Native Swedish speakers
You will not qualify if you...
- Dementia or a score less than 19 on the Montreal Cognitive Assessment (MOCA) or Mini Mental State Examination (MMSE)
- Presence of other neurological disorders
- Ongoing psychosis
- Ongoing alcohol or drug addiction
- Severe problems with vision or hearing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a series of social cognition tests and evaluations of cognitive, psychiatric, and motor functions.
1 assessment visit (in-person)
Trial Site Locations
Total: 1 location
1
Skane University Hospital, Region Skane
Lund, Sweden, 22184
Actively Recruiting
Research Team
A
Asa Petersen, MD, PhD
I
Isak Halling, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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