Actively Recruiting
Examining Olive Oil Extract on Knee Comfort and Function
Led by Applied Food Sciences Inc. · Updated on 2026-04-15
168
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
Sponsors
A
Applied Food Sciences Inc.
Lead Sponsor
A
Alethios, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to learn if an olive oil extract works to improve knee pain and discomfort in adults. The main questions it aims to answer are: 1) Does the olive oil extract improve the perceptions of knee pain and discomfort, and 2) Does the olive oil extract improve knee function in adults? The main procedures in the study include: * Screening and informed consent * Take one assigned study capsule (supplement or placebo) daily with food for 6 weeks * Complete digital questionnaires about your knee pain, stiffness, and function at scheduled times * Complete a Day 1 acute assessment and two simple functional movement tests at home as described below * If possible, connect a compatible wearable device to allow collection of sleep and physical activity data as detailed below. * Collect saliva samples at home using a provided kit at designated timepoints * Record any pain medications taken during the study or any side effects
CONDITIONS
Official Title
Examining Olive Oil Extract on Knee Comfort and Function
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 40 to 75 years
- Self-reported knee discomfort lasting at least 3 months
- Willing and able to take one study capsule daily for 6 weeks
- Willing and able to complete digital questionnaires and functional movement tasks using the Alethios platform
- Willing and able to wear a compatible activity-tracking device throughout the study
- Willing and able to collect saliva samples at home using a provided kit, if applicable
- Able to read and understand English
- Willing to provide informed consent electronically
You will not qualify if you...
- Diagnosis of inflammatory joint disease or other systemic inflammatory conditions affecting the knee
- Any current or prior diagnosis of knee disease by a licensed medical provider
- Knee surgery or significant knee injury within the past 6 months
- Planned knee surgery during the study period
- Known allergy or sensitivity to olive-derived products or any study product ingredients
- Current use of investigational drugs or participation in another research study during this study
- Any medical condition or circumstance that might make participation unsafe or affect study data quality
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Alethios, Inc.
San Francisco, California, United States, 94104
Actively Recruiting
Research Team
C
Christine Fields, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here