Study of Exercise and Dietary Counselling to Lower Cardiovascular Risk in Adults with Kidney Transplants

What this Trial Is About

This research aims to determine if tailored exercise combined with dietary counselling can reduce cardiovascular risk in adult kidney transplant recipients compared to standard care over a 3-year observation period. The study also explores how lifestyle changes may affect kidney function, quality of life, gut microbiota, inflammatory markers, and cardiovascular biomarkers in this patient group. Participants are randomly assigned to one of two groups the intervention group receives a personalized exercise program along with specific dietary counselling, while the control group receives general advice on healthy lifestyles without tailored prescriptions. Throughout the study, researchers will monitor several health indicators including cardiovascular risk scores, kidney function, gut microbiota composition, inflammatory and cardiovascular biomarkers, and quality of life. Participants will be followed for three years during which they will undergo regular assessments of their health status, biomarkers, and lifestyle adherence. The study will also track hospital admissions, cardiovascular events, and mortality. Data on the cost-effectiveness of the lifestyle intervention will be collected, and participants overall wellbeing and biological markers will be measured to evaluate the impact of the interventions.

Exercise and Diet Effects in Reducing Cardiovascular Risk in Kidney Transplant Recipients